DNA fragmentation test

Maintaining the integrity of the sperm's genetic structure is important for normal fertilization and a healthy embryo. Sometimes the sperm does not have a chromosome number change such as aneuploidy, but instead the sperm's DNA structure is disrupted. Such a pathological change is not detected in a normal spermogram analysis. It is not detected in spermogram analysis. It is recommended to check the quality of sperm DNA in men whose spermogram analysis results are normal. For this, sperm DNA fragmentation analysis is performed. In such patients, repeated miscarriages, repeated failed artificial insemination, low quality embryos and repeated failed implantation occur in pregnancy. However, even if the embryos formed from the fertilization of an egg cell with a spermatozoon with DNA fragmentation detected do not cause a problem in pregnancy, theoretically, these children are at high risk of developing cancer after birth.

DNA fragmentation test instructions:

• In infinity of unknown cause

• Couples with problems with embryo formation

• Recurrent miscarriages

• Men over 45 years old

• Recurrent unsuccessful artificial insemination (IVF/ICSI)

• If there is an abnormal embryo during the use of assisted reproductive methods

Additionally, in the following cases, Sperm DNA fragmentation test can be added to the screening and check up.

• Smoking, age factor

• Sexual infections, high fever diseases

• Varicocele, dirty environment effect

Temperature increase in the testicles: infectious causes, epidemic parotitis (mumps).