Factor V Leiden is a specific mutation in the Factor V gene. This mutation prevents the Factor V protein from breaking down as it normally does, making the blood clotting process more active. As a result, the risk of blood clots increases, which can lead to serious medical problems, such as deep vein thrombosis and pulmonary embolism. Factor V Leiden mutation is inherited in an autosomal dominant manner and can be heterozygous or homozygous.
