The FV Seoul-2 mutation is a rare genetic change in the Factor V gene. This mutation affects the Factor V protein and makes the blood clotting process more active. As a result, the risk of clotting increases, which can lead to serious medical problems such as deep vein thrombosis and pulmonary embolism. The FV Seoul-2 mutation is inherited in an autosomal dominant manner and is associated with a high risk of blood clotting.
Although the clinical effects of this mutation are similar to those of Factor V Leiden and other Factor V mutations, FV Seoul-2 is a specifically distinct genetic change.
