ID:
G1078
HLA B5/B51/B52 Behçet's disease
Method:
Human Leukocyte Antigens
Full name:
Comprehensive diagnosis of HLA B5/B51/B52 Behçet's disease genetic markers
Sample Type:
Sample quantity:
Sample container:
Blood
5 ml
A tube with a purple cap
Behçet's disease is a rare, chronic, and systemic vasculitis that causes inflammation and scarring in various parts of the body. HLA-B5, HLA-B51, and HLA-B52 alleles have been associated with genetic risk of Behçet's disease, particularly HLA-B51. Below are the symptoms and description of Behçet's disease:
Behçet's disease
Description: Behcet's disease is a chronic disease mainly seen in young adults. In this disease, vascular inflammation occurs in different parts of the body and affects several systems.
Mouth Sores:
The most common symptom of Behçet's disease is recurrent mouth ulcers (aphthous stomatitis). These sores are painful and sometimes take several weeks to heal.
Genital Sores:
Painful sores are also observed in the genitals. After these wounds heal, scar tissue may remain.
Skin Problems:
A variety of skin lesions develop, such as erythema nodosum and red and painful nodules. Acne-like rashes may also appear.
Eye Problems:
Uveitis (inflammation of the middle layer of the eye) and inflammation of other parts of the eye is one of the serious complications of Behcet's disease. This condition can cause vision loss.
Joints:
Joint pain and swelling (arthritis) is also common, especially in the knees, ankles and wrists.
Neurological Problems:
Headache, meningitis-like symptoms, and inflammation of the brain and spinal cord (encephalomyelitis) may be signs of neurological involvement.
Vascular Problems:
Behçet's disease can affect both arteries and veins. Inflammation of blood vessels and the risk of blood vessel blockage increases.
Digestive System:
Symptoms such as abdominal pain, diarrhea and bloody stools can be inflammatory bowel disease.