ID:
G1081
HLA B5/B52 genetic marker of Behçet's disease and Takayasu's arthritis

Method:
Human Leukocyte Antigens
Full name:
HLA B5/B52 genetic marker of Behçet's disease and Takayasu's arthritis
Sample Type:
Sample quantity:
Sample container:
Blood
5 ml
A tube with a purple cap
HLA B5/B52 alleles are recognized as genetic markers of certain autoimmune diseases, including Behçet's disease and Takayasu's arteritis. Both of these diseases are characterized by the immune system attacking the body's own cells.
Behçet's disease
Behçet's disease is a rare autoimmune disease that causes inflammation in various systems.
Takayasu's Arthritis
Takayasu's arthritis is a rare type of vasculitis characterized by inflammation of the large vessels, particularly the aorta and its major branches.
Symptoms of Behcet's disease:
Mouth Sores:
The most common symptom of Behçet's disease is recurrent mouth ulcers (aphthous stomatitis). These sores are painful and sometimes take several weeks to heal.
Genital Sores:
Painful sores are also observed in the genitals. After these wounds heal, scar tissue may remain.
Skin Problems:
Various skin lesions appear, such as erythema nodosum, red and painful nodules. Acne-like rashes may also appear.
Eye Problems:
Uveitis (inflammation of the middle layer of the eye) and inflammation of other parts of the eye is one of the serious complications of Behcet's disease. This condition can cause vision loss.
Joints:
Joint pain and swelling (arthritis) is also common, especially in the knees, ankles and wrists.
Neurological Problems:
Headache, meningitis-like symptoms, and inflammation of the brain and spinal cord (encephalomyelitis) may be signs of neurological involvement.
Vascular Problems:
Behçet's disease can affect both arteries and veins. Inflammation of blood vessels and the risk of blood vessel blockage increases.
Digestive System:
Symptoms such as abdominal pain, diarrhea and bloody stools can be inflammatory bowel disease.
Symptoms of Takayasu Arthritis:
Main Symptoms
Extreme Fatigue : A drop in energy levels.
Multiform Flu : Fever, night sweats, and weight loss.
Vascular Problems : Weak pulse, blood pressure differences due to narrowing or blockage of veins.
Extremity Pain and Weakness : Pain, weakness in arms or legs.
Chest Pain : Heart problems such as angina (chest pain) or myocardial infarction.
Other Symptoms
Eye Problems : Iritis, uveitis or inflammation of retinal vessels.
Nephritis : Kidney inflammation, decreased kidney function.
Central Nervous System Problems : Headache, visual disturbances and cerebrovascular events.